BDBM50063453 1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-pyridin-4-yl-ethanone::CHEMBL66699

SMILES Clc1ccc2[C@H](N3CCN(CC3)C(=O)Cc3ccncc3)c3ncccc3CCc2c1

InChI Key InChIKey=QIVUVRPLLRMTDC-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063453   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063453(1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063453(1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclo...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed