BDBM50063629 3-[3-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-ureido]-benzoic acid methyl ester::CHEMBL9449

SMILES COC(=O)c1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)c1

InChI Key InChIKey=QEERNRLHWXBDMM-QFIPXVFZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063629   

TargetCholecystokinin receptor type A(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063629(3-[3-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063629(3-[3-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor from rat pancreas using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50063629(3-[3-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  8nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063629(3-[3-((R)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed