BDBM50063979 5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL23054

SMILES COc1ccc(OC)c(c1)N(C)Cc1coc2nc(N)nc(N)c12

InChI Key InChIKey=VQKKJBBJXLPRIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063979   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063979(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-f...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063979(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-f...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063979(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-f...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis carniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed