BDBM50064171 1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]::1'-benzylspiro[chroman-2,4'-piperidine]::CHEMBL38634

SMILES C(N1CCC2(CC1)CCc1ccccc1O2)c1ccccc1

InChI Key InChIKey=CRKWADRIYCMTBU-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50064171   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi:  0.617nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi:  0.620nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]-NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]-prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]-prazosin from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]-spiperone from rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-NMS from rat heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed