BDBM50064797 (3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-methoxy-benzyl)-piperazine-2,5-dione::CHEMBL29897

SMILES COc1ccc(CN2[C@@H](CC3CCCCC3)C(=O)N[C@@H](CS)C2=O)cc1

InChI Key InChIKey=QAKAOVFKLDKHAW-ROUUACIJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064797   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  79nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  79nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed