BDBM50065396 (R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-ethanesulfonylamino-propionamide::CHEMBL89008

SMILES CCS(=O)(=O)N[C@H](COCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=YQBJQKXVOBLSJT-VQTJNVASSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065396   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065396((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-eth...)
Affinity DataIC50:  400nMAssay Description:Inhibition of intracellular Calpain-I receptor using intact cell assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed