BDBM50065454 CHEBI:63453::CHEMBL3348846
SMILES COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1
InChI Key InChIKey=VRQMAABPASPXMW-HDICACEKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50065454
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of recombinant FGFR3 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of FGFR1 in human H1581 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: <0.200nMAssay Description:Inhibition of FGFR1 in human KG1 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of FGFR2 in human KATO III cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FGFR3 in human RT112 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Chinese Academy Of Sciences (Cas)
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair