BDBM50065792 (E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl-quinolin-8-yl ester::CHEMBL432775

SMILES COc1ccc(\C=C\C(=O)Oc2cccc3ccc(C)nc23)cc1OC

InChI Key InChIKey=CPHKRMYYWIZKOQ-FMIVXFBMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065792   

TargetIntegrase(Human immunodeficiency virus 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro anti-HIV integrase activity of the compound was tested against integration(strand transfer) of target plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50065792((E)-3-(3,4-Dimethoxy-phenyl)-acrylic acid 2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:HIV integrase inhibitory potency of the compound was evaluated as IC50 on 3' processing of target DNA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed