BDBM50066066 (S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidin-1-yl]-3-(3,4-difluoro-phenoxy)-propan-2-ol::1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidin-1-yl]-3-(3,4-difluoro-phenoxy)-propan-2-ol(Lubeluzole)::CHEMBL281724::LUBELUZOLE
SMILES CN(C1CCN(C[C@H](O)COc2ccc(F)c(F)c2)CC1)c1nc2ccccc2s1
InChI Key InChIKey=OZFSWVOEXHGDES-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50066066
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataKi: 203nMAssay Description:Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge Neuroscience
Curated by ChEMBL
Cambridge Neuroscience
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair