BDBM50066336 (S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 2,5-dichloro-benzylamide::(S)-1-(2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 2,5-dichloro-benzylamide::CHEMBL42495

SMILES N[C@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1Cl

InChI Key InChIKey=IKGYVUZSXPRLMO-ZWKOTPCHSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50066336   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  5nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  5nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease TPA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  2.90E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  4.90E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  5.86E+5nMAssay Description:Binding affinity of the compound was evaluated on serine protease plasma kallikrein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066336((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  6.91E+5nMAssay Description:Binding affinity of the compound was evaluated on serine protease plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed