BDBM50066374 (2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL109926

SMILES CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)\C=C/C)C(O)=O)c1cc2OCOc2c(OC)c1

InChI Key InChIKey=GHDYDXZRKIXRDK-RDXXDGPGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066374   

TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066374((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dim...)
Affinity DataIC50:  4.53E+4nMAssay Description:Binding affinity for endothelin B receptor by measuring its ability to displace [125I]-ET-3 from porcine cerebellar tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066374((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dim...)
Affinity DataIC50:  0.290nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066374((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dim...)
Affinity DataIC50:  0.410nMAssay Description:Binding affinity for endothelin A receptor by measuring its ability to displace [125I]-ET-1 from prolactin secreting rat pituitary cells(MMQ)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066374((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dim...)
Affinity DataIC50:  3.97E+4nMAssay Description:Tested for binding affinity for human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed