BDBM50066436 2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-dione::2-(2,6-dimethylphenyl)-5-hydroxyisoindoline-1,3-dione::CHEMBL424612

SMILES Cc1cccc(C)c1N1C(=O)c2ccc(O)cc2C1=O

InChI Key InChIKey=GPUARNPEQNPVEX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066436   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  7.41E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  3.74E+4nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  7.48E+4nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066436(2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-di...)
Affinity DataIC50:  7.41E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed