BDBM50066614 (E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-one::2,7-di[1-[4-amino(imino)methylphenyl]-(E)-methylidene]-1-cycloheptanone::CHEMBL48233
SMILES NC(=N)c1ccc(\C=C2/CCCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1
InChI Key InChIKey=BGRKMKHJBDYTGS-IWGRKNQJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50066614
Affinity DataKi: 0.660nMAssay Description:Compound was tested for inhibition activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Compound was tested for inhibition activity against bovine trypsin.More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:In vitro inhibition of bovine trypsin(Trp).More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin.More data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Compound was tested for inhibition activity against human thrombin (FIIa)More data for this Ligand-Target Pair
Affinity DataKi: 610nMAssay Description:Inhibition of bovine factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:In vitro inhibition of human thrombin(FIIa).More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:In vitro inhibition of human coagulation factor Xa (Xa) in a purified enzyme system.More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Compound (isomer) was tested in the absence of light for inhibitory activity against Human Coagulation factor XMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Helsinki
Curated by ChEMBL
University Of Helsinki
Curated by ChEMBL
Affinity DataIC50: 484nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair