BDBM50066633 3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-methyl-pyridin-2-yloxy]-N,N-dimethyl-benzamide::CHEMBL70730

SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1

InChI Key InChIKey=WBQTWIMCPJDTPA-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50066633   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  80nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  80nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  80nMAssay Description:Compound was tested for inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  80nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was tested for inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibitory potency was measured against bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi: >5.00E+3nMAssay Description:Compound was tested for inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066633(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibitory potency was measured against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed