BDBM50066727 CHEMBL3403129

SMILES Nc1cnc2sc(c(-c3cnccc3Cl)c2c1)S(=O)(=O)c1cc(F)cc(c1)C#N

InChI Key InChIKey=SIEMIPOWYQFRNR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066727   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066727(CHEMBL3403129)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066727(CHEMBL3403129)
Affinity DataIC50:  34nMAssay Description:Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed