BDBM50067772 CHEMBL343369::Rhenium complex of 3-(2-Bromo-2,2,2-triformyl-3-methyl-1lambda*4*,2lambda*6*,3lambda*4*-[1,2,3]dithiolan-1-yl)-propionic acid 3-(4-fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ylmethyl ester

SMILES CN1C2CCC1[C@@H](COC(=O)CC[S+]1CC[S+](C)[Re]1(Br)(C=O)(C=O)C=O)[C@H](C2)c1ccc(F)cc1

InChI Key InChIKey=HJNJANKWHZHFSJ-BTZBKTBQSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067772   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(CHEMBL343369 | Rhenium complex of 3-(2-Bromo-2,2,2...)
Affinity DataIC50:  0.146nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(CHEMBL343369 | Rhenium complex of 3-(2-Bromo-2,2,2...)
Affinity DataIC50:  20nMAssay Description:The compound was tested in vitro for low binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(CHEMBL343369 | Rhenium complex of 3-(2-Bromo-2,2,2...)
Affinity DataIC50:  72nMAssay Description:The compound was tested in vitro for binding affinity for the serotonin transporter (5-HTT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50067772(CHEMBL343369 | Rhenium complex of 3-(2-Bromo-2,2,2...)
Affinity DataIC50:  7.30nMAssay Description:The compound was tested in vitro for binding affinity for the norepinephrine transporter (NET) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed