BDBM50067971 2-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phenyl-piperidine::CHEMBL332284

SMILES FC(F)(F)c1cc(COCC2(CCCCN2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=SDAQMMFVBYMJDD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067971   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067971(2-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phen...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]SAr-Met from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067971(2-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phen...)
Affinity DataIC50:  1nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067971(2-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phen...)
Affinity DataIC50:  1nMAssay Description:Binding affinity at human tachykinin receptor 1 by measuring its ability to displace [125I]-labeled substance P from the cloned receptor expressed in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed