BDBM50068280 5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester::CHEMBL341885

SMILES O=C(CCCCNC(=O)OCc1ccccc1)OCN1C(=O)c2ccccc2S1(=O)=O

InChI Key InChIKey=YPSXMLHFZYLLMR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50068280   

TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity was measured against urokinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibitory activity was measured against human leukocyte elastase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibitory activity was measured against plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068280(5-Benzyloxycarbonylamino-pentanoic acid 1,1,3-trio...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibitory activity was measured against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed