BDBM50068479 (2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane::CHEMBL421777

SMILES CN1[C@@H]2CCC1[C@@H]([C@@H](C2)c1ccc(C)cc1)c1ccccc1

InChI Key InChIKey=YJWQTICONBXOHT-JGUMPVPUSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50068479   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  173nMAssay Description:Binding affinity on dopamine and serotonin transporters in striated membranes using [3H]- paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  287nMAssay Description:Binding affinity for Serotonin transporter was determined by [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  314nMAssay Description:Inhibitory activity against Serotonin transporter was determined for [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  4.5nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068479((2S,3R,5R)-8-Methyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibitory activity on dopamine and serotonin transporters in striated membranes using [3H]- paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed