BDBM50068482 (2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane::CHEMBL148419

SMILES CCC[C@H]1C2CC[C@H](C[C@H]1c1ccc(C)cc1)N2C

InChI Key InChIKey=QCRUGFCHRLZVTK-HRBLRVMOSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50068482   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  12nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  50nMAssay Description:Binding affinity for Serotonin transporter was determined by [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50068482((2R,3R,5R)-8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against Serotonin transporter was determined for [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed