BDBM50069070 (5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7,8,9,9a,10-octahydro-pyrido[2,3-b]carbazol-2-one::CHEMBL161892

SMILES CN1[C@@H]2CCCC[C@@H]2c2cc3c(cc(=O)n(C)c3cc12)C(F)(F)F

InChI Key InChIKey=MCZDFWOPLACFDA-QMTHXVAHSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50069070   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataKi:  10nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataIC50:  36nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonistic activity against hPR in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity against Glucocorticoid receptor in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069070((5bR,9aR)-1,10-Dimethyl-4-trifluoromethyl-1,5b,6,7...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity against hMR in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed