BDBM50069076 (R)-2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetrahydro-pyrrolo[3,2-g]quinolin-7-one::CHEMBL165219

SMILES C[C@H]1Nc2cc3[nH]c(=O)cc(c3cc2C1(C)C)C(F)(F)F

InChI Key InChIKey=GVRLVMHEBSAKOX-SSDOTTSWSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069076   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069076((R)-2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetr...)
Affinity DataKi:  21nMAssay Description:Binding affinity against Androgen receptor transfected into COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069076((R)-2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetr...)
Affinity DataIC50:  48nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069076((R)-2,3,3-Trimethyl-5-trifluoromethyl-1,2,3,8-tetr...)
Affinity DataEC50:  99nMAssay Description:Agonistic activity (EC50) against human androgen receptor (hAR) in cotransfected CV-1 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed