BDBM50069226 CHEMBL265216::{(S)-4-[(R)-2-((R)-1-Hydroxy-1-hydroxycarbamoyl-ethyl)-5-phenyl-pentanoylamino]-4-methylcarbamoyl-butyl}-carbamic acid tert-butyl ester

SMILES CNC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)[C@H](CCCc1ccccc1)[C@@](C)(O)C(=O)NO

InChI Key InChIKey=SJPBXYWXFIQQJH-XHNVNVPESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069226   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069226(CHEMBL265216 | {(S)-4-[(R)-2-((R)-1-Hydroxy-1-hydr...)
Affinity DataKi:  2nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069226(CHEMBL265216 | {(S)-4-[(R)-2-((R)-1-Hydroxy-1-hydr...)
Affinity DataKi:  13nMAssay Description:Binding affinity against human matrix metalloproteinase-3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069226(CHEMBL265216 | {(S)-4-[(R)-2-((R)-1-Hydroxy-1-hydr...)
Affinity DataKi:  16nMAssay Description:Binding affinity was evaluated against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed