BDBM50069355 (1-{(R)-1-{3-[(E)-2-(6,7-Dihydro-5H-[1]pyrindin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::(R)-2-(1-((1-(3-(2-(6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetic acid::CHEMBL143515

SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCc3n2)c1

InChI Key InChIKey=YPGHWRLRDCDOMY-ILZHQVLHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069355   

TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50069355((1-{(R)-1-{3-[(E)-2-(6,7-Dihydro-5H-[1]pyrindin-2-...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed