BDBM50069367 (1-{(R)-1-{3-[(E)-2-(5-Ethyl-6-methyl-pyridin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid::(R)-2-(1-((1-(3-(2-(5-ethyl-6-methylpyridin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetic acid::CHEMBL345093
SMILES CCc1ccc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)nc1C
InChI Key InChIKey=PJVNGFRHENPVNP-ILZHQVLHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50069367
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair