BDBM50069465 CHEMBL343863::Thiophene-2-carboxylic acid (7-bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amide

SMILES Brc1cc(CNC(=O)c2cccs2)c2[nH]c(=O)c(=O)[nH]c2c1

InChI Key InChIKey=QAKGVBTUMLAEFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069465   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50069465(CHEMBL343863 | Thiophene-2-carboxylic acid (7-brom...)
Affinity DataIC50:  10nMAssay Description:In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50069465(CHEMBL343863 | Thiophene-2-carboxylic acid (7-brom...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]MDL from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50069465(CHEMBL343863 | Thiophene-2-carboxylic acid (7-brom...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]AMPA from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed