BDBM50069567 3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL10218
SMILES CCCOc1ccc2n(Cc3ccc4OCOc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1
InChI Key InChIKey=LQWGCVIETCFLOP-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50069567
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125I]-ET-1 binding to porcine kidney inner medulla membrane Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]-ET-1 binding to rat aorta membrane Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Potency of the compound at Endothelin A receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of contraction of ET-1 induced rabbit femoral artery, which are known to express predominantly ETA receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against Endothelin B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair