BDBM50069833 3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-pyridine::CHEMBL86079

SMILES CCCc1cncc(OC[C@@H]2CCCN2C)c1

InChI Key InChIKey=SCCWLILDZVYJOK-ZDUSSCGKSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069833   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069833(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-p...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069833(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-p...)
Affinity DataIC50:  3.20E+3nMAssay Description:Stimulation of cation efflux in human nAChR alpha4-beta2 expressing K177 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069833(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-p...)
Affinity DataEC50: >1.00E+6nMAssay Description:Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069833(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-p...)
Affinity DataIC50:  2.40E+3nMAssay Description:Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed