BDBM50070097 (Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6,7-dihydroindolizin-8(5H)-one::6-(4-Chloro-phenyl)-7-[1-pyridin-4-yl-meth-(Z)-ylidene]-6,7-dihydro-5H-indolizin-8-one::CHEMBL9165::MR-20492

SMILES Clc1ccc(cc1)C1Cn2cccc2C(=O)\C1=C/c1ccncc1

InChI Key InChIKey=OMGJLQMHGRFTAP-ATVHPVEESA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070097   

TargetAromatase(Homo sapiens (Human))
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...)
Affinity DataKi:  10nMAssay Description:Inhibition constant for human aromatase cytochrome P450 19A1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human aromatase cytochrome P450 19A1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Centre D'Etudes Et De Recherche Sur Le MéDicament De Normandie

Curated by ChEMBL
LigandPNGBDBM50070097((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...)
Affinity DataIC50:  150nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed