BDBM50070886 CHEMBL51234::Sodium; (Z)-2-benzo[1,2,5]thiadiazol-5-yl-4-(3-chloro-4-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate

SMILES COc1ccc(cc1Cl)C(=O)C(\Cc1cc(OC)c(OC)c(OC)c1)=C(/C([O-])=O)c1ccc2nsnc2c1

InChI Key InChIKey=GAKQDXZHZRHZNZ-ULJHMMPZSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070886   

TargetEndothelin-1 receptor(RAT)
Merck

Curated by ChEMBL
LigandPNGBDBM50070886(CHEMBL51234 | Sodium; (Z)-2-benzo[1,2,5]thiadiazol...)
Affinity DataIC50:  1nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to rat aorta membranes Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Merck

Curated by ChEMBL
LigandPNGBDBM50070886(CHEMBL51234 | Sodium; (Z)-2-benzo[1,2,5]thiadiazol...)
Affinity DataIC50:  180nMAssay Description:In vitro ability to inhibit specific [125I]ET1 binding to porcine kidney (inner medulla) membranes Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed