BDBM50071220 2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine::CHEMBL64671

SMILES COc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1

InChI Key InChIKey=SBXMILAGIXPXOK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50071220   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50:  490nMAssay Description:Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50:  17nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071220(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Affinity DataIC50:  700nMAssay Description:Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed