BDBM50071325 CHEMBL3410210
SMILES Cc1ccc(cc1)C#Cc1ncn-2c1COc1ccccc-21
InChI Key InChIKey=KYFAZBYUDNHGIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50071325
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataKi: 2.84E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair