BDBM50071377 CHEMBL3407528
SMILES CN1Cc2c(ncn2-c2ccc(F)cc2C1=O)C#Cc1ccccc1
InChI Key InChIKey=LMXUGQJMQSMLIQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50071377
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataKi: 368nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 295nMAssay Description:Negative allosteric modulation of mGlu5 (unknown origin) expressed in HEK293 cells assessed as inhibition of L-AP4-induced calcium mobilization incub...More data for this Ligand-Target Pair