BDBM50071392 (E)-2-Cyano-3-hydroxy-but-2-enethioic acid (4-trifluoromethyl-phenyl)-amide::CHEMBL70544

SMILES CC(=O)C(C#N)C(=S)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=CQFSFPNSCXPPOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071392   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50071392((E)-2-Cyano-3-hydroxy-but-2-enethioic acid (4-trif...)
Affinity DataIC50:  800nMAssay Description:Immunosuppressive activity of the compound expressed as ability to inhibit human recombinant dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed