BDBM50071542 (S)-3-(2-Acetylamino-3-methyl-butyrylamino)-5-[2-(2,6-dichloro-phenyl)-acetoxy]-4-oxo-pentanoic acid::CHEMBL78154

SMILES CC(C)C(NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)COC(=O)Cc1c(Cl)cccc1Cl

InChI Key InChIKey=PQNJYNTYQQZVFE-FUKCDUGKSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071542   

TargetCaspase-1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071542((S)-3-(2-Acetylamino-3-methyl-butyrylamino)-5-[2-(...)
Affinity DataKi:  82nMAssay Description:Compound was tested for inhibitory activity against N-His (D381E) Interleukin -1 beta converting enzyme (resynthesized compound)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071542((S)-3-(2-Acetylamino-3-methyl-butyrylamino)-5-[2-(...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for binding affinity against N-His (D381E) Interleukin -1 beta converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071542((S)-3-(2-Acetylamino-3-methyl-butyrylamino)-5-[2-(...)
Affinity DataIC50:  5nMAssay Description:Compound was tested for inhibitory activity against N-His (D381E) Interleukin -1 beta converting enzyme (combinatorially prepared compound)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed