BDBM50071920 Birinapant::TL-32711

SMILES CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1C[C@@H](O)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1[nH]c2cc(F)ccc2c1C[C@@H]1C[C@H](O)CN1C(=O)[C@H](CC)NC(=O)[C@H](C)NC

InChI Key InChIKey=PKWRMUKBEYJEIX-DXXQBUJASA-N

Data  1 IC50  4 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50071920   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataIC50:  50nMAssay Description:Binding affinity to human N-terminal His-tagged cIAP1 BIR2-3 C202A/C213G mutant after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  36nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
Australian National University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataEC50:  300nMAssay Description:Inhibition of Zika virus NS2B-NS3 protease by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  1nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 7(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  1nMAssay Description:Binding affinity to ML-IAP-BIR domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  50nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair