BDBM50072047 4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((S)-2-hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-2-methyl-propylcarbamoyl]-butyric acid::CHEMBL430648

SMILES CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=SKSZJGAFHISZNB-JZRNZGBLSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50072047   

TargetCaspase-1(Mus musculus)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against Caspase-1 using Ac-TyrValAlaAsp-amc as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against human Caspase-3 using Ac-AspGluValAsp as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration of compound required against Caspase-8 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of compound required against Caspase-7 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory concentration of compound required against Caspase-3 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of compound required against Caspase-6 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072047(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-((...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration of compound required against Caspase-1 enzyme compared to acylated dipeptidesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed