BDBM50072229 (1R,3S,4R)-3-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,2,5]thiadiazol-3-yl]-1-aza-bicyclo[2.2.1]heptane::CHEMBL99884

SMILES C(Sc1nsnc1[C@@H]1C[N@@]2CC[C@H]1C2)C#Cc1ccccc1

InChI Key InChIKey=WEDQUQGOGGNBGS-LSDHHAIUSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072229   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072229((1R,3S,4R)-3-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataEC50:  139nMAssay Description:Stimulation of cAMP in CHO cells expressing human m2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50072229((1R,3S,4R)-3-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataIC50:  42nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072229((1R,3S,4R)-3-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Affinity DataEC50: >100nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed