BDBM50072566 (2R,3S)-2-Allyl-N*4*-[(S)-1-benzyl-2-(1H-indol-3-yl)-2-oxo-ethyl]-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL432991
SMILES CC(C)C[C@H]([C@H](CC=C)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)c1c[nH]c2ccccc12
InChI Key InChIKey=PJKWYBIJVPNFJI-FBLLAGFSSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50072566
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1 isolated from the culture medium of human skin fibroblasts induced with PMAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase 7More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human MMP7 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PMA-induced human skin fibroblast derived MMP1 by fluorometric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TNF-induced MMP2 isolated from human HT-1080 cell medium by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 2 isolated from human HT-1080 fibrosarcoma cells induced with TNFMore data for this Ligand-Target Pair