BDBM50072704 5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL112987

SMILES CCCCC1Oc2ccc(Cl)cc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=KJSHBZLXBZYVMR-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50072704   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072704(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072704(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataKi:  394nMAssay Description:Displacement of Dexamethasone from human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072704(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataKi:  886nMAssay Description:Displacement of DHT from human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072704(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072704(5-Butyl-9-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed