BDBM50072706 5-Butyl-8-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL321243

SMILES CCCCC1Oc2cc(F)ccc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=KTYXHEXVPYONGV-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072706   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072706(5-Butyl-8-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataKi:  27nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072706(5-Butyl-8-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataEC50:  5.29E+3nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072706(5-Butyl-8-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...)
Affinity DataEC50:  538nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed