BDBM50072710 2,2,4-Trimethyl-5-propylsulfanyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL114611

SMILES CCCSC1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=KXZQVMAYYXKOIF-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072710   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072710(2,2,4-Trimethyl-5-propylsulfanyl-2,5-dihydro-1H-6-...)
Affinity DataKi:  24nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072710(2,2,4-Trimethyl-5-propylsulfanyl-2,5-dihydro-1H-6-...)
Affinity DataEC50:  187nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072710(2,2,4-Trimethyl-5-propylsulfanyl-2,5-dihydro-1H-6-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed