BDBM50072711 5-(4-Chloro-butyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL332264

SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CCCCCl)c3c12

InChI Key InChIKey=YRVFOAARONPYKD-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072711   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072711(5-(4-Chloro-butyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072711(5-(4-Chloro-butyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  33nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072711(5-(4-Chloro-butyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed