BDBM50073123 (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonanoylamino]-3-phenyl-propionic acid ethyl ester::CHEMBL108294

SMILES CCCCCCC(NC(=O)c1ccc(cc1)C#N)C(C)(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCC

InChI Key InChIKey=MXDAOEAHZKUMCQ-PMCHYTPCSA-N

Data  1 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50073123   

TargetChymotrypsinogen A(Bos taurus (bovine))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataKi:  4.5nMAssay Description:Compound was evaluated for inactivation of bovine alpha-Chymotrypsin Kinetic constant(Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  540nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  8.70nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  8.40nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  8.70nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Bos taurus)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  220nMAssay Description:Compound was tested by chromogenic assay for the inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Bos taurus)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  8.60nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Porcine ElastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  0.700nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Porcine ElastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Bos taurus)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  220nMAssay Description:Compound was tested by chromogenic assay for the inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  8.60nMAssay Description:Compound was tested by chromogenic assay for the inhibition of serine proteases like Porcine ElastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50:  440nMAssay Description:Compound was tested by chromogenic assay for the inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed