BDBM50073429 CHEMBL82032::CHEMBL84575::N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide

SMILES NC(=N)N1CCC[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O

InChI Key InChIKey=PIIUKKBKYNGKMK-NBJLRHFZSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50073429   

TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  101nMAssay Description:In vitro inhibitory activity of the compound was evaluated against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity of the compound was evaluated against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  0.710nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  23nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  0.710nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  152nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed