BDBM50073886 4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic acid [(S)-2-phenyl-1-(pyridin-3-ylcarbamoyl)-ethyl]-amide::CHEMBL293018

SMILES CCO[C@H]1CC[C@](CS)(CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cccnc1

InChI Key InChIKey=CGYJGYNVEBFJEL-AWRGLXIESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073886   

TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  135nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073886(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed