BDBM50073891 4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic acid [(S)-2-(4-fluoro-phenyl)-1-phenylcarbamoyl-ethyl]-amide::CHEMBL60951

SMILES CCO[C@H]1CC[C@](CS)(CC1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)Nc1ccccc1

InChI Key InChIKey=ZYDVQCXEFCLUHX-WRALFONMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073891   

TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073891(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  134nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073891(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  6.26E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073891(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  83nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed