BDBM50073899 4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic acid [(S)-2-phenyl-1-(4-trifluoromethoxy-phenylcarbamoyl)-ethyl]-amide::CHEMBL413270

SMILES CCO[C@H]1CC[C@](CS)(CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=QHKXZDFWYMKYHX-UWDQQESISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073899   

TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073899(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  81nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073899(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50:  175nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073899(4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic ac...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed