BDBM50074154 Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-2-ylmethyl}-amine::CHEMBL159683

SMILES CN(C[C@@H]1CCCN1CCc1c[nH]c2ccc(cc12)-n1cnnc1)Cc1ccccc1

InChI Key InChIKey=DABOBNYSAYZCKM-QHCPKHFHSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074154   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074154(Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataEC50:  3nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074154(Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074154(Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed