BDBM50074219 8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carboxylic acid propyl ester::CHEMBL348766

SMILES CCCOC(=O)c1c2CCSC(=O)c2c(CC)nc1-c1ccccc1

InChI Key InChIKey=NJPFUDJNLIHKEL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074219   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074219(8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3...)
Affinity DataKi:  248nMAssay Description:Displacement of specific [125 I]AB-MECA binding at human Adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074219(8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3...)
Affinity DataKi:  2.58E+3nMAssay Description:Displacement of specific [125I]-AB-MECA binding at rat Adenosine A3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074219(8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3...)
Affinity DataKi:  1.65E+4nMAssay Description:Displacement of specific [3H]-CGS- 21680R-PIA binding to Adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50074219(8-Ethyl-1-oxo-6-phenyl-3,4-dihydro-1H-thiopyrano[3...)
Affinity DataKi:  6.71E+4nMAssay Description:Inhibition of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed